Community Q&A
Our Region Browser lets you interpret any variant in its genomic and functional context. In addition to static annotations, you can:
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Visualise gene structure in relation to your variant.
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Review coverage and read-quality metrics across the region to identify artefacts or confirm variant support.
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Explore population and clinical databases (ClinVar, gnomAD, DGV, etc.) alongside your variant of interest.
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Compare with known pathogenic and benign variants to support interpretation.
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Investigate neighboring features like nearby genes, pseudogenes, or repetitive elements that may influence classification.
Whether you’re assessing a CNV breakpoint or a splice-site SNV, the Region Browser gives you the context needed to make confident, evidence-based decisions.
Browser interface settings
There are four icons on the right-hand side, which can be used to maximize the browser, save the current position in the browser, and change various display settings.
General settings:
Full screen mode: You have the option to select the size of the genome browser window.
- Native full-screen window
- Expand to current window size
Theme: You can select the theme of the genome browser component. Note that by selecting the system theme, the theme is adjusted to the one you have chosen from the background setting option on your browser.
Zoom speed: The option to adjust the speed while zooming in/out inside the genome browser window (default = 1x).
Color scales: You can choose the colors/color scales for every track in the different browsers, e.g., Conservation and Pathogenicity on the genome region browser and sample view. Click on the drop-down menu of the track that you want to change, and select one of the predefined palette options.
Gesture control options:
- Hold Ctrl and scroll to zoom: Use CTRL + SCROLL to zoom in/out
- Click to activate scroll zoom: Use SCROLL to zoom in/out
Watch the short video below to see these settings in action.
For more information on our Region Browser, please visit our Help Center.
