---
title: VarSome Premium now with OncoKB™ Integration
description: VarSome Premium now integrates OncoKB™, offering evidence-based insights into the clinical actionability of somatic variants for precision oncology.
image: https://blog.varsome.com/hubfs/ONCOKB%20ft%20im.png
---
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VarSome.com VarSome.com Premium VarSome in Action
# VarSome Premium now with OncoKB™ Integration
Jason Armstrong
September 8, 2025
We are pleased to announce that OncoKB™, the precision oncology knowledgebase developed by Memorial Sloan Kettering Cancer Center, is now integrated directly into VarSome Premium (version 13.9.0).
OncoKB™ provides curated, evidence-based information on the oncogenic effect and clinical actionability of cancer variants. By incorporating OncoKB™ into VarSome Premium, we give users a faster, more confident route to understanding the therapeutic, diagnostic, and prognostic relevance of somatic variants within our renowned, intuitive interface.
This integration enhances the interpretation of somatic variants by:
- Flagging clinically actionable variants with therapy implications, biomarker associations, or diagnostic relevance, mapped to cancer types.
- Providing structured evidence levels in line with FDA and AMP/ASCO/CAP guidelines, helping laboratories align with regulatory standards.
- Supporting treatment decisions with links to FDA-approved drugs, guidelines, and relevant clinical trials.
Combined with VarSome’s existing annotation layers, OncoKB™ data helps prioritize variants with the greatest clinical significance. Users can instantly see whether a variant is associated with a targeted therapy or relevant resistance mechanism, reducing the time spent cross-referencing databases and increasing confidence in reporting.
OncoKB™ data is now also available via the VarSome API, enabling seamless integration into automated somatic workflows.
The addition of OncoKB™ aligns with our continuing goal at Saphetor: to support precision oncology workflows that are faster, clearer, and more clinically useful. If you have any questions, please feel free to contact us at [sales@varsome.com](mailto:sales@varsome.com) or by [clicking here.](https://share.hsforms.com/1ZmUY0j_7Q9KDAlmIiewGBw2lysh) Otherwise, take a look at the clip below to see OncoKB™ in action!
## Share this post
[mailto:https%3A%2F%2Fblog.varsome.com%2Fannotated%2Fvarsome-premium-oncokb-integration](mailto:https%3A%2F%2Fblog.varsome.com%2Fannotated%2Fvarsome-premium-oncokb-integration)
## Keep reading
### [ VarSome Annotated Minor Spliceosome Defects Drive Monogenic Autoimmune Diabetes](https://blog.varsome.com/annotated/minor-spliceosome-defects-drive-monogenic-autoimmune-diabetes)
### [ VarSome Annotated Promoter Editing and Fetal Hemoglobin Reactivation in Sickle Cell Disease](https://blog.varsome.com/annotated/promoter-editing-and-fetal-hemoglobin-reactivation-in-sickle-cell-disease)
---
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